Importin 9 Antikörper (AA 601-729)

Produktnummer ABIN873167

Produktdetails anti-Importin 9 Antikörper

Target: Importin 9 (IPO9)

Bindungsspezifität: AA 601-729

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Importin 9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Importin 9

Target: Importin 9 (IPO9)

Andere Bezeichnung: Importin 9 (IPO9 Produkte)

Synonyme: Imp9 antikoerper, 0710008K06Rik antikoerper, AI845704 antikoerper, C78347 antikoerper, Ranbp9 antikoerper, mKIAA1192 antikoerper, zgc:66429 antikoerper, wu:fc23d12 antikoerper, MGC81741 antikoerper, IPO9 antikoerper, DDBDRAFT_0205722 antikoerper, DDBDRAFT_0229883 antikoerper, DDB_0205722 antikoerper, DDB_0229883 antikoerper, RGD1561940 antikoerper, RanBPM antikoerper, RanBP9 antikoerper, bpm-l antikoerper, bpm90 antikoerper, ranbp9 antikoerper, ranbp9-a antikoerper, ranbp9-b antikoerper, ranbp9b antikoerper, cb457 antikoerper, zgc:158650 antikoerper, importin 9 antikoerper, importin 9 L homeolog antikoerper, RAN binding protein 9 antikoerper, RAN binding protein 9 L homeolog antikoerper, IPO9 antikoerper, Ipo9 antikoerper, ipo9 antikoerper, ipo9.L antikoerper, cnrP antikoerper, Ranbp9 antikoerper, ranbp9.L antikoerper, RANBP9 antikoerper, ranbp9 antikoerper

Hintergrund:

Synonyms: B cell antigen receptor Ig beta associated protein 1, BPM 90, BPM L, BPM-L, BPM90, BPML, IBAP 1, Imp 9, Importin 9, Importin9, Importin-9, Novel centrosomal protein RanBPM, RAN binding protein 9, Ran binding protein centrosomal, Ran binding protein M, Ran BP9, Ran-binding protein 9, Ran-binding protein M, RANB9_HUMAN, RanBP 7, RANBP 9, RanBP7, RanBP9, RanBPM.

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.

Gen-ID: 10048

Pathways: Protein targeting to Nucleus