ALOX15B Antikörper (AA 13-110)

Produktnummer ABIN873138

Dieser Anti-ALOX15B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ALOX15B in ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Ratte.

Kurzübersicht für ALOX15B Antikörper (AA 13-110) (ABIN873138)

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX15B Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ALOX15B Antikörper

Bindungsspezifität: AA 13-110

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ALOX15B/15 Lipoxygenase 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ALOX15B

Target: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Andere Bezeichnung: ALOX15B

Hintergrund:

Synonyms: 15-LOX-2, Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-lipoxygenase 2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-LOb, ALOX15B

Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

Gen-ID: 247

UniProt: O15296