LAP3 Antikörper (AA 131-230)

Produktnummer ABIN872975

Produktdetails anti-LAP3 Antikörper

Target: LAP3 (Cytosol Aminopeptidase (LAP3))

Bindungsspezifität: AA 131-230

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAP3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LAP3

Target: LAP3 (Cytosol Aminopeptidase (LAP3))

Andere Bezeichnung: LAP3 (LAP3 Produkte)

Synonyme: LAP antikoerper, LAPEP antikoerper, PEPS antikoerper, 2410015L10Rik antikoerper, AA410100 antikoerper, LAP-3 antikoerper, Lap antikoerper, Lapep antikoerper, Pep-7 antikoerper, Pep-S antikoerper, Pep7 antikoerper, Peps antikoerper, cytosol aminopeptidase antikoerper, leucine aminopeptidase 3 antikoerper, pepA antikoerper, Plabr_1567 antikoerper, Dester_0800 antikoerper, Weevi_0186 antikoerper, Marky_0570 antikoerper, Halhy_2623 antikoerper, FsymDg_3217 antikoerper, Flexsi_2186 antikoerper, Runsl_3980 antikoerper, lap3 antikoerper, LAP3 antikoerper, Lap3 antikoerper

Hintergrund:

Synonyms: Cytosol aminopeptidase, LAP 3, LAP, LAPEP, Leucine aminopeptidase 3, Leucyl aminopeptidase, PEPS, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase, AMPL_HUMAN.

Background: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Gen-ID: 51056