Biglycan Antikörper (AA 101-200)

Produktnummer ABIN872817

Dieses Anti-Biglycan-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Biglycan in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human, Ratte, Maus und Kaninchen. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Biglycan Antikörper (AA 101-200) (ABIN872817)

Target: Biglycan (BGN)

Reaktivität: Human, Ratte, Maus, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Biglycan Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Biglycan Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human, Maus, Kaninchen, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Biglycan

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Biglycan Antikörper (ABIN872817)

Han, Wang, Jiang, Ma, Tian, Zang, Ma: "An Animal Model of Modic Changes by Embedding Autogenous Nucleus Pulposus inside Subchondral Bone of Lumbar Vertebrae." in: Scientific reports, Vol. 6, pp. 35102, (2016) (PubMed).

Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).

Details zu Biglycan

Target: Biglycan (BGN)

Andere Bezeichnung: Biglycan

Hintergrund:

Synonyms: PGI, DSPG1, PG-S1, SLRR1A, Biglycan, Bone/cartilage proteoglycan I, BGN

Background: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

Gen-ID: 633

UniProt: P21810

Pathways: Glycosaminoglycan Metabolic Process