Adrenomedullin 2 Antikörper (AA 121-180)

Produktnummer ABIN872804

Der Kaninchen Polyklonal Anti-Adrenomedullin 2-Antikörper wurde für ELISA, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, Adrenomedullin 2 in Proben von Human zu detektieren.

Kurzübersicht für Adrenomedullin 2 Antikörper (AA 121-180) (ABIN872804)

Target: Adrenomedullin 2 (ADM2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adrenomedullin 2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Adrenomedullin 2 Antikörper

Bindungsspezifität: AA 121-180

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AMID/AIFM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Adrenomedullin 2

Target: Adrenomedullin 2 (ADM2)

Andere Bezeichnung: AM2

Hintergrund:

Synonyms: am2, AM2_HUMAN, AMID, Apoptosis inducing factor A homologous mitochondrion associated inducer of death, Apoptosis inducing factor A like mitochondrion associated inducer of death, Apoptosis inducing factor mitochondrion associated 2, Apoptosis-inducing factor 2, Apoptosis-inducing factor homologous mitochondrion-associated inducer of death, Apoptosis-inducing factor-like mitochondrion-associated inducer of death, Cys51Stop, p53 responsive gene 3 p53 tumor suppressor p53-responsive gene 3 protein PRG3 TRP53 Tumor protein p53.

Background: Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.Tissue specificity: Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells.

Gen-ID: 84883

Pathways: Hormone Activity, Feeding Behaviour