GTPase, IMAP Family Member 3 Pseudogene (GIMAP3P) (AA 1-100) Antikörper
Kurzübersicht für GTPase, IMAP Family Member 3 Pseudogene (GIMAP3P) (AA 1-100) Antikörper (ABIN872685)
Target
Alle GTPase, IMAP Family Member 3 Pseudogene (GIMAP3P) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Kreuzreaktivität
- Ratte
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Homologie
- Mouse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse GIMAP3
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- GTPase, IMAP Family Member 3 Pseudogene (GIMAP3P)
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Andere Bezeichnung
- Gimap3
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Hintergrund
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Synonyms: GTPase, IMAP family member 3 pseudogene, Ian4, Gimap5, 2010110D23Rik, GIMAP 3, GIMAP3, GTPase IMAP family member 3, GTPase of the immune associated protein 3, Immune associated nucleotide 4, Immunity associated nucleotide 4 protein.
Background: GIMAP3p is a murine mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The IAN/GIMAP family consists of GTP-binding proteins that share a unique primary structure and whose expression is finely regulated by T-cell receptor signals. Recent studies have shown that IAN/GIMAP family proteins crucially regulate the survival of T cells during development, selection and homeostasis, and are possibly linked to the onset of T-lymphopenia, leukemia and autoimmunity. IAN/GIMAP family proteins might also take part in mitochondrial regulation of lymphocyte apoptosis by interacting with Bcl-2 family proteins. The human GIMAP (GTPase of the immunity-associated protein) gene family includes seven functional members residing on (human) chromosome 7q36.1 and one pseudogene (hGIMAP3).
Target
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