Der Kaninchen Polyklonal Anti-CSNK2A1/CK II alpha-Antikörper wurde für WB validiert. Er ist geeignet, CSNK2A1/CK II alpha in Proben von Human, Maus und Ratte zu detektieren.
The antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.
Aufreinigung
Affinity purified
Immunogen
Peptide sequence around phosphorylation site of pThr360, pSer362 (V-P-T (p) -P-S (p) -P-L) derived from Human CK2a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
CSNK2A1/CK II alpha (CSNK2A1)
(Casein Kinase 2 alpha 1 (CSNK2A1))
Andere Bezeichnung
CK2alpha
Hintergrund
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.