Specific for a core protein epitope (aa220-233) of human glypi-can- 4. Glypican-4, previously known as K-glypican, is a GPI-linked cell surface heparan sulfate proteoglycan of the glypican gene family, that comprises 6 members at present. Its function is only partially understood at present. However, glypican-4 seems to be involved in the control of cell growth and diffe-rentiation, especially in the development of the central nervous system and the kidney. Furthermore, glypican-4 is expressed by hematopoetic stem cells and bone marrow stromal cells. Although the antiserum was prepared against a peptide from human glypican-4, due to the highly conserved structure and sequence of glypican-4, it might react also with glypican-4 from other species, like mouse.
GPC4
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Westernblot (1:1000), Immunohistochemistry (1:1000) This antibody has not been tested for use in all applications. This does not necessarily exclude its use for non-tested procedures. The stated dilutions are recommendations only.