Estrogen Receptor alpha Antikörper (C-Term)
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- Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Bindungsspezifität
- AA 580-594, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Anti-ER (Estrogen Receptor)
- Spezifität
- ER (Estrogen Receptor)
- Immunogen
- Peptide derived from C-terminal sequence of human estrogen receptor alpha. Antibody recognizes the epitope between Gln580 - Thr594.
- Klon
- S21-V
- Isotyp
- IgG
- Top Product
- Discover our top product ESR1 Primärantikörper
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- Applikationshinweise
- 1:100 - 200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- +2 °C to +8 °C
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- Target
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Andere Bezeichnung
- Estrogen Receptor (ESR1 Produkte)
- Hintergrund
- Estrogen Receptor- α antibody stains nuclei of breast epithelial cells and some carcinomas, as well as endometrial epithelia and myometrium. By binding to the DNA, estrogen receptor-α regulates positively or negatively the gene expression. ER plays an important role in regulation of mammary gland growth and differentiation. Its overexpression can be found in more than 70 % of breast cancer.
- UniProt
- P03372
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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