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Estrogen Receptor alpha Antikörper (C-Term)

ESR1 Reaktivität: Human IHC (p) Wirt: Kaninchen Monoclonal S21-V unconjugated
Produktnummer ABIN870440
  • Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Bindungsspezifität
    • 29
    • 27
    • 26
    • 24
    • 22
    • 21
    • 15
    • 15
    • 15
    • 15
    • 15
    • 14
    • 14
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 580-594, C-Term
    Reaktivität
    • 435
    • 161
    • 149
    • 15
    • 15
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 350
    • 92
    • 1
    Kaninchen
    Klonalität
    • 330
    • 114
    • 1
    Monoklonal
    Konjugat
    • 194
    • 31
    • 21
    • 18
    • 15
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
    Applikation
    • 316
    • 148
    • 135
    • 102
    • 87
    • 80
    • 74
    • 49
    • 29
    • 27
    • 22
    • 15
    • 9
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Anti-ER (Estrogen Receptor)
    Spezifität
    ER (Estrogen Receptor)
    Immunogen
    Peptide derived from C-terminal sequence of human estrogen receptor alpha. Antibody recognizes the epitope between Gln580 - Thr594.
    Klon
    S21-V
    Isotyp
    IgG
    Top Product
    Discover our top product ESR1 Primärantikörper
  • Applikationshinweise
    1:100 - 200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    +2 °C to +8 °C
  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Andere Bezeichnung
    Estrogen Receptor (ESR1 Produkte)
    Hintergrund
    Estrogen Receptor- α antibody stains nuclei of breast epithelial cells and some carcinomas, as well as endometrial epithelia and myometrium. By binding to the DNA, estrogen receptor-α regulates positively or negatively the gene expression. ER plays an important role in regulation of mammary gland growth and differentiation. Its overexpression can be found in more than 70 % of breast cancer.
    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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