MUC1 Antikörper (C-Term)
Kurzübersicht für MUC1 Antikörper (C-Term) (ABIN870416)
Target
Alle MUC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1235-1253, C-Term
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Verwendungszweck
- Anti-EMA (CD227, Mucin-1)
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Spezifität
- EMA (CD227, Mucin
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Immunogen
- Peptide derived from C-terminal sequence of human Mucin-1. Antibody recognizes the epitope between Gly1235 - Ala1253.
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Isotyp
- IgG
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Applikationshinweise
- IHC-P 1:100 - 200, IHC-Fr 1:400-600
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- +2 °C to +8 °C
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- MUC1 (Mucin 1 (MUC1))
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Andere Bezeichnung
- EMA
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Hintergrund
- Anti-EMA antibody is a useful marker for staining several types of carcinomas. It stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squamous epithelium. Hepatocellular carcinoma, adrenal carcinoma and embryonal carcinomas are consistently EMA negative, so keratin positivity with negative EMA favors one of these tumors. EMA is frequently positive in meningiomas, breast, ovary, lung and prostate tumors.
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UniProt
- P15941
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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