Neuropilin 1 Antikörper

Produktnummer ABIN866080

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Neuropilin 1 in WB und ICC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Neuropilin 1 Antikörper (ABIN866080)

Target: Neuropilin 1 (NRP1)

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuropilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Klon: 10-D9

Produktdetails anti-Neuropilin 1 Antikörper

Spezifität: This antibody is produced by immunizing mouse with recombinant protein Neuropilin-1.

Kreuzreaktivität: Maus

Produktmerkmale: Positive Control: Recombinant protein. Cellular Localization: Cell membrane, secretory protein

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB 1:1,000~1:2,000. ICC 1:100~1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.17mg/ml

Buffer: 1xTBS (pH7.4), 0.5% BSA, 25% Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Neuropilin 1

Target: Neuropilin 1 (NRP1)

Andere Bezeichnung: Neuropilin-1

Hintergrund: Neuropilin-1 is a single-pass type I membrane protein, which has two isoforms. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. The soluble isoform 2 binds VEGF-165 (vascular endothelial growth factor165) and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. Its expression has an averse effect on blood vessel number and integrity.

Molekulargewicht: 47kDa

UniProt: P97333

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals