OCT4 Antikörper

Produktnummer ABIN865484

Der Maus Monoklonal anti-OCT4 Antikörper wird verwendet zum Nachweis von OCT4 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für OCT4 Antikörper (ABIN865484)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OCT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 5F7

Produktdetails anti-OCT4 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Synthesized peptide of human Oct4.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100g/100l

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Andere Bezeichnung: OCT4

Hintergrund: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.. Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. Synonyms: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, MGC22487, POU5F1

Molekulargewicht: 45kDa

Gen-ID: 5460

Pathways: Stem Cell Maintenance