SLC5A5 Antikörper (AA 468-643)
Kurzübersicht für SLC5A5 Antikörper (AA 468-643) (ABIN863184)
Target
Alle SLC5A5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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                                            Bindungsspezifität
- AA 468-643
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                                            Spezifität
- Detects ~97 kDa, non-glycosylated version at 68 kDa. Other minor bands associated with hNIS at 160 kDa, and degradation products at ~30 kDa, and ~15 kDa.
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                                            Kreuzreaktivität
- Human, Maus, Ratte
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                                            Aufreinigung
- Protein G Purified
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                                            Immunogen
- Mannose binding protein hNIS fusion (AA468-643)
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                                            Isotyp
- IgG1 kappa
 
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    - 
                                            Applikationshinweise
- 
                        - WB (1:1000)
- IHC (1:1000)
- optimal dilutions for assays should be determined by the user.
 
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                                            Kommentare
- 
                        1 μg/ml of ABIN863184 was sufficient for detection of hNIS in 20 μg of transfected COS-7 cell membrane lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 1 mg/mL
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                                            Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- -20°C
 
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    - SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
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                                            Andere Bezeichnung
- Sodium Iodide Symporter
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                                            Hintergrund
- The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3).
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                                            Gen-ID
- 6528
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                                            NCBI Accession
- NP_000444
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                                            UniProt
- Q92911
 Target
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