MDC1 Antikörper (N-Term)

Produktnummer ABIN863114

This anti-MDC1 antibody (ABIN863114) is a Mouse Monoclonal antibody detecting MDC1 in WB, IF, ICC. Suitable for Mouse.

Quick Overview for MDC1 Antikörper (N-Term) (ABIN863114)

Target: MDC1 (Mdc1 (MDC1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: P2B11

Produktdetails anti-MDC1 Antikörper

Bindungsspezifität: N-Term

Spezifität: Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.

Kreuzreaktivität: Schimpanse, Rind (Kuh), Human, Maus

Aufreinigung: Protein G Purified

Immunogen: GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:2000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

0.5 μg/ml of ABIN863114 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu MDC1

Target: MDC1 (Mdc1 (MDC1))

Andere Bezeichnung: MDC1

Hintergrund: MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.

Gen-ID: 240087

NCBI Accession: NP_001010833

UniProt: Q5PSV9