MDC1 Antikörper (N-Term)
Kurzübersicht für MDC1 Antikörper (N-Term) (ABIN863114)
Target
Alle MDC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Bindungsspezifität
- N-Term
- 
                                            Spezifität
- Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
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                                            Kreuzreaktivität
- Schimpanse, Rind (Kuh), Human, Maus
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                                            Aufreinigung
- Protein G Purified
- 
                                            Immunogen
- GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
- 
                                            Isotyp
- IgG1
 
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- 
    - 
                                            Applikationshinweise
- 
                        - WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
 
- 
                                            Kommentare
- 
                        0.5 μg/ml of ABIN863114 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis. 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- -20°C
 
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    - MDC1 (Mdc1 (MDC1))
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                                            Andere Bezeichnung
- MDC1
- 
                                            Hintergrund
- MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
- 
                                            Gen-ID
- 240087
- 
                                            NCBI Accession
- NP_001010833
- 
                                            UniProt
- Q5PSV9
 Target
- 
                    
 
                                     
                                     
                                    