Piccolo Antikörper
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- Target Alle Piccolo (PIC) Produkte
- Piccolo (PIC)
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Piccolo Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- Detects ~550 kDa. No cross-reactivity to Bassoon.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Full length recombinant protein (GenBank ID: BC001304.1)
- Klon
- 6H9-B6
- Isotyp
- IgG2b kappa
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anti-Piccolo (PIC) (AA 2011-2350) antibody
PIC Reaktivität: Ratte, Maus WB, IHC, ICC Wirt: Meerschweinchen Polyclonal unconjugated
anti-Piccolo (PIC) antibodyPIC Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Piccolo (PIC) antibody (HRP)PIC Reaktivität: Maus WB, ELISA, ICC, IF Wirt: Maus Monoclonal 6H9-B6 HRP
anti-Piccolo (PIC) antibody (FITC)PIC Reaktivität: Maus WB, ELISA, ICC, IF Wirt: Maus Monoclonal 6H9-B6 FITC
anti-Piccolo (PIC) antibody (HRP)PIC Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal HRP
anti-Piccolo (PIC) antibody (Biotin)PIC Reaktivität: Maus WB, ELISA, ICC, IF Wirt: Maus Monoclonal 6H9-B6 Biotin
anti-Piccolo (PIC) antibody (PE)PIC Reaktivität: Maus WB, ELISA, ICC, IF Wirt: Maus Monoclonal 6H9-B6 PE
anti-Piccolo (PIC) antibody (FITC)PIC Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal FITC
anti-Piccolo (PIC) antibody (APC)PIC Reaktivität: Maus WB, ELISA, ICC, IF Wirt: Maus Monoclonal 6H9-B6 APC
anti-Piccolo (PIC) antibody (PerCP)PIC Reaktivität: Maus WB, ELISA, ICC, IF Wirt: Maus Monoclonal 6H9-B6 PerCP
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN863104 was sufficient for detection of Piccolo in 20 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C
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- Target
- Piccolo (PIC)
- Andere Bezeichnung
- Piccolo (PIC Produkte)
- Hintergrund
- Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).
- Gen-ID
- 26875
- NCBI Accession
- NP_001104266
- UniProt
- Q9QYX7
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