JUP Antikörper (pTyr550)

Produktnummer ABIN802488

Dieses Anti-JUP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von JUP in ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für JUP Antikörper (pTyr550) (ABIN802488)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-JUP Antikörper

Bindungsspezifität: pTyr550

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human JUP around the phosphorylation site of Tyr550

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: JUP

Hintergrund:

Synonyms: gamma Catenin phospho Y550, p-gamma Catenin phospho Y550, catenin cadherin-associated protein gamma 80kD, Catenin gamma, CTNNG, Desmoplakin 3, Desmoplakin III, Desmoplakin3, DesmoplakinIII, DP 3, DP III, DP3, DPIII, gamma catenin, Junction plakoglobin, JUP, PDGB, PKGB, PLAKOGLOBIN.

Background: Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

Gen-ID: 3728

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location