MAX Antikörper (pTyr123) (Biotin)

Produktnummer ABIN801890

Der Kaninchen Polyklonal Anti-MAX-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, MAX in Proben von Human zu detektieren.

Kurzübersicht für MAX Antikörper (pTyr123) (Biotin) (ABIN801890)

Target: MAX (MYC Associated Factor X (MAX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAX Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MAX Antikörper (Biotin)

Bindungsspezifität: pTyr123

Homologie: Human,Mouse,Rat,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MAX protein around the phosphorylation site of Tyr123

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MAX

Target: MAX (MYC Associated Factor X (MAX))

Andere Bezeichnung: MAX protein

Hintergrund:

Synonyms: bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, Class D basic helix-loop-helix protein 4, Helix loop helix zipper protein, MAX protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, Myc associated factor X, Myc-associated factor X, MAX_HUMAN, Myc binding novel HLH/LZ protein, Orf 1, Orf1, Protein max.

Background: MAX protein is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Gen-ID: 4149

Pathways: Mitotic G1-G1/S Phases