GRIN2B Antikörper (pTyr1252)
Kurzübersicht für GRIN2B Antikörper (pTyr1252) (ABIN801213)
Target
Alle GRIN2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr1252
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Spezifität
- This antibody may cross react with NMDAR2A (Tyr 1246) due to 75 % sequence similarity.
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Homologie
- Human,Mouse,Dog,Cow,Chicken,Rabbit,Guinea Pig
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252
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Isotyp
- IgG
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 27-163) antibody
GRIN2B Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 6E9A8 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (HRP)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (FITC)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 FITC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Biotin)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 Biotin
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PE)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 PE
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (APC)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 APC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PerCP)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 PerCP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 488)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 Atto 488
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 594)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 Atto 594
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 390)GRIN2B Reaktivität: Ratte WB, IHC, IP, IF, ICC, AA Wirt: Maus Monoclonal S59 Atto 390
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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Andere Bezeichnung
- NMDAR2B
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Hintergrund
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NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Subcellular location: Cell membrane
Synonyms: MRD6, NR2B, hNR3, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NR3, GRIN2B
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Gen-ID
- 2904
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UniProt
- Q13224
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Pathways
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
Target
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