GABBR1 Antikörper (pSer923) (HRP)

Produktnummer ABIN800892

Dieses Anti-GABBR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GABBR1 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human, Ratte und Maus.

Kurzübersicht für GABBR1 Antikörper (pSer923) (HRP) (ABIN800892)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GABBR1 Antikörper (HRP)

Bindungsspezifität: pSer923

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse GABBR1 around the phosphorylation site of Ser923

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Gentamicin sulfate

Vorsichtsmaßnahmen: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: Gabbr1

Hintergrund:

Synonyms: GABBR1 phospho S1180, GABBR1 phospho Ser1180, p-GABBR1 Ser1180, GABAb Receptor 1, dJ271M21.1.1, dJ271M21.1.2, FLJ92613, GAB B R1, GABA B R1, GABAB R1, GABAB subunit 1c, GABAB1e, GABABR 1, GABABR1, GABB R1, GABBR 1, GABBR1 3, GABBR1, Gamma aminobutyric acid GABA B receptor 1, Gamma aminobutyric acid B receptor 1, Gamma aminobutyric acid type B receptor subunit 1, Gb 1, Gb1, GPRC 3A, GPRC3A, hGB1a, GABR1_HUMAN, Gamma-aminobutyric acid type B receptor subunit 1, GABA B Receptor 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, Seven transmembrane helix receptor.

Background: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

Gen-ID: 54393

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process