GABBR1 Antikörper (pSer923) (Biotin)

Produktnummer ABIN800885

Der Kaninchen Polyklonal Anti-GABBR1-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, GABBR1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für GABBR1 Antikörper (pSer923) (Biotin) (ABIN800885)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GABBR1 Antikörper (Biotin)

Bindungsspezifität: pSer923

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse GABBR1 around the phosphorylation site of Ser923

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: Gabbr1

Hintergrund:

Synonyms: GABBR1 phospho S1180, GABBR1 phospho Ser1180, p-GABBR1 Ser1180, GABAb Receptor 1, dJ271M21.1.1, dJ271M21.1.2, FLJ92613, GAB B R1, GABA B R1, GABAB R1, GABAB subunit 1c, GABAB1e, GABABR 1, GABABR1, GABB R1, GABBR 1, GABBR1 3, GABBR1, Gamma aminobutyric acid GABA B receptor 1, Gamma aminobutyric acid B receptor 1, Gamma aminobutyric acid type B receptor subunit 1, Gb 1, Gb1, GPRC 3A, GPRC3A, hGB1a, GABR1_HUMAN, Gamma-aminobutyric acid type B receptor subunit 1, GABA B Receptor 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, Seven transmembrane helix receptor.

Background: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

Gen-ID: 54393

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process