CD41, CD61 Antikörper (FITC)
Kurzübersicht für CD41, CD61 Antikörper (FITC) (ABIN784613)
Target
Alle CD41, CD61 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ion Exchange or Affinity Chromatography.
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Immunogen
- Human platelets. Hybridization of Sp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, pH 7.2 containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- This product is photosensitive and should be protected from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- CD41, CD61 (CD41,CD61)
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Hintergrund
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
Target
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