CD41, CD61 Antikörper (FITC)

Produktnummer ABIN784613

Der Maus-Monoklonal Anti-CD41, CD61-Antikörper wurde für FACS validiert. Er ist geeignet zum Nachweis von CD41, CD61 in Proben aus Human. }

Kurzübersicht für CD41, CD61 Antikörper (FITC) (ABIN784613)

Target: CD41, CD61 (CD41,CD61)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD41, CD61 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: P2

Produktdetails anti-CD41, CD61 Antikörper (FITC)

Aufreinigung: Ion Exchange or Affinity Chromatography.

Immunogen: Human platelets. Hybridization of Sp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2 containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Hintergrund: Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb