CD41, CD61 Antikörper

Produktnummer ABIN784612

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD41, CD61 in FACS, IP, EIA, IHC (fro) und Func. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD41, CD61 Antikörper (ABIN784612)

Target: CD41, CD61 (CD41,CD61)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD41, CD61 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: P2

Produktdetails anti-CD41, CD61 Antikörper

Immunogen: Human platelets

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water.

Konzentration: 0.2 mg/mL (prior to lyophilization)

Buffer: PBS buffer with 1 mg/mL BSA as stabilizer without preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Hintergrund: Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb