CD41, CD61 Antikörper

Produktnummer ABIN784612

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD41, CD61 in FACS, IP, EIA, IHC (fro) und Func. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD41, CD61 Antikörper (ABIN784612)

Target: CD41, CD61 (CD41,CD61)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD41, CD61 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: P2

Produktdetails anti-CD41, CD61 Antikörper

Immunogen: Human platelets

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water.

Konzentration: 0.2 mg/mL (prior to lyophilization)

Buffer: PBS buffer with 1 mg/mL BSA as stabilizer without preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Hintergrund: Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb