Histone H4 Antikörper (acLys5)

Produktnummer ABIN784593

Dieses Anti-Histone H4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Histone H4 in WB, IF, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Histone H4 Antikörper (acLys5) (ABIN784593)

Target: Histone H4

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Histone H4 Antikörper

Bindungsspezifität: acLys5

Spezifität: This antibody detects endogenous levels of total Histone H4 protein only when acetylated at Lysine5.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human Histone H4 around the acetylated site of Lys5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containig 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu Histone H4

Target: Histone H4

Hintergrund: Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.Synonyms: H4/A, H4FA, HIST1H4

Gen-ID: 121504

NCBI Accession: NP_001029249