Der Kaninchen Polyklonal anti-Botulinum Neurotoxin Type A Antikörper wird verwendet zum Nachweis von Botulinum Neurotoxin Type A in Proben von Clostridium botulinum. Er wurde validiert für EIA.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.52 mg/mL (OD280nm, E0.1% = 1.4)
Buffer
PBS containing 20 % Glycerol, None
Konservierungsmittel
Azide free
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Target
Botulinum Neurotoxin Type A (BoNTA)
Andere Bezeichnung
Botulinum Neurotoxin Type A
Hintergrund
Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A