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ZEB2 Antikörper (C-Term)
ZEB2
Reaktivität: Human, Maus, Ratte
WB, IF, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-ZEB2 Antikörper
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Target
Alle ZEB2 Antikörper anzeigen
ZEB2
(Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
Bindungsspezifität
Alle Epitope für ZEB2 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für ZEB2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für ZEB2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ZEB2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für ZEB2 Antikörper
Dieser ZEB2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ZEB2 Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to the C-term of ZEB2.
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Immunoaffinity Chromatography
Immunogen
ZEB2 antibody was raised against an 18 amino acid synthetic near the carboxy terminus of Human ZEB2.
Isotyp
IgG
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu ZEB2
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Target
ZEB2
(Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
Andere Bezeichnung
ZFHX1B (ZEB2 Produkte )
Synonyme
ZFHX1B antikoerper, Zfhx1b antikoerper, HSPC082 antikoerper, SIP-1 antikoerper, SIP1 antikoerper, SMADIP1 antikoerper, 9130203F04Rik antikoerper, D130016B08Rik antikoerper, Zfx1b antikoerper, Zfxh1b antikoerper, mKIAA0569 antikoerper, XSip1 antikoerper, sip1 antikoerper, zfhx1b antikoerper, si:dkey-52o2.2 antikoerper, sip1a antikoerper, wu:fc92g08 antikoerper, sip1b antikoerper, zinc finger E-box binding homeobox 2 antikoerper, zinc finger E-box binding homeobox 2 S homeolog antikoerper, zinc finger homeobox protein antikoerper, zinc finger E-box binding homeobox 2a antikoerper, zinc finger E-box binding homeobox 2b antikoerper, ZEB2 antikoerper, Zeb2 antikoerper, zeb2.S antikoerper, zeb2 antikoerper, zeb2a antikoerper, zeb2b antikoerper
Hintergrund
ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues. Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.Synonyms: KIAA0569, SIP1, SMADIP1, Smad-interacting protein 1, ZEB2, ZFX1B, Zinc finger E-box-binding homeobox 2, Zinc finger homeobox protein 1b
Gen-ID
9839
NCBI Accession
NP_001165124
Pathways
Tube Formation
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