TXNDC11 Antikörper (Internal Region)

Produktnummer ABIN783977

Produktdetails anti-TXNDC11 Antikörper

Target: TXNDC11 (Thioredoxin Domain Containing 11 (TXNDC11))

Bindungsspezifität: AA 113-126, Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TXNDC11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-QLDYAEYVRR DSE

Spezifität: Recognizes TXNDC11 (113-126).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_056998.4. Genename: TXNDC11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TXNDC11

Target: TXNDC11 (Thioredoxin Domain Containing 11 (TXNDC11))

Andere Bezeichnung: TXNDC11 (TXNDC11 Produkte)

Synonyme: EFP1 antikoerper, 2810408E11Rik antikoerper, AI427833 antikoerper, Txdc11 antikoerper, RGD1307538 antikoerper, thioredoxin domain containing 11 antikoerper, TXNDC11 antikoerper, Txndc11 antikoerper

Hintergrund: TXNDC11 May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA. 3 isoforms of the human protein are produced by alternative splicing.Synonyms: EF-hand-binding protein 1, EFP1, Thioredoxin domain-containing protein 11

Gen-ID: 51061

NCBI Accession: NP_056998

Pathways: Cell RedoxHomeostasis