ITIH4 Antikörper (C-Term)

Produktnummer ABIN783974

Der Ziege Polyklonal anti-ITIH4 Antikörper wird verwendet zum Nachweis von ITIH4 in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für ITIH4 Antikörper (C-Term) (ABIN783974)

Target: ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ITIH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-ITIH4 Antikörper

Bindungsspezifität: AA 890-903, C-Term

Sequenz: C-SDDGRRTLRV QGND

Spezifität: This antibody is expected to recognize both reported isoforms (NP_002209.2, NP_001159921.1).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_002209.2 and NP_001159921.1. Genename: ITIH4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ITIH4

Target: ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))

Andere Bezeichnung: ITIH4

Hintergrund: The inter-a-trypsin inhibitor (ITI, IaI) family, a typical and classical example for protein-glycosaminoglycanprotein (PGP) complexes, occurs constitutively in plasma at relatively high concentrations and is a result of alternate combinations of three kinds of heavy chains with a common light chain, the bikunin proteoglycan. Bikunin has two proteinase inhibitor domains and belongs to the Kunitz-type protease inhibitor family, it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.Synonyms: Gp120, IHRP, ITI heavy chain H4, ITI-HC4, ITIHL1, Inter-alpha-inhibitor heavy chain 4, Inter-alpha-trypsin inhibitor family heavy chain-related protein, Inter-alpha-trypsin inhibitor heavy chain H4, PK120, Plasma kallikrein sensitive glycoprotein 120

Gen-ID: 216

NCBI Accession: NP_002209

Pathways: Glycosaminoglycan Metabolic Process