Fascin 2 Antikörper (Internal Region)
Kurzübersicht für Fascin 2 Antikörper (Internal Region) (ABIN783923)
Target
Alle Fascin 2 (FSCN2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Sequenz
- CHHRGSNQLD TNR
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Spezifität
- This antibody is expected to recognize both reported isoforms (NP_001070650.1 and NP_036550.1).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Dog.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity Chromatgraphy
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Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_001070650.1, NP_036550.1. Genename: FSCN2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Fascin 2 (FSCN2)
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Andere Bezeichnung
- Fascin-2
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Hintergrund
- Fascin-2 Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.Synonyms: FSCN2, Retinal fascin
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Gen-ID
- 25794
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NCBI Accession
- NP_001070650
Target
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