Fascin 2 Antikörper (Internal Region)

Produktnummer ABIN783923

Produktdetails anti-Fascin 2 Antikörper

Target: Fascin 2 (FSCN2)

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Fascin 2 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: CHHRGSNQLD TNR

Spezifität: This antibody is expected to recognize both reported isoforms (NP_001070650.1 and NP_036550.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatgraphy

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001070650.1, NP_036550.1. Genename: FSCN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Fascin 2

Target: Fascin 2 (FSCN2)

Andere Bezeichnung: Fascin-2 (FSCN2 Produkte)

Synonyme: fascin-2 antikoerper, A930022G03 antikoerper, C630046B20Rik antikoerper, ahl8 antikoerper, RFSN antikoerper, RP30 antikoerper, fascin actin-bundling protein 2, retinal antikoerper, fascin actin-bundling protein 1 antikoerper, fascin actin-bundling protein 2 antikoerper, FSCN2 antikoerper, FSCN1 antikoerper, Fscn2 antikoerper

Hintergrund: Fascin-2 Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.Synonyms: FSCN2, Retinal fascin

Gen-ID: 25794

NCBI Accession: NP_001070650