Transmembrane Protein 18 (TMM18) (C-Term) Antikörper

Produktnummer ABIN783829

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Transmembrane Protein 18 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Transmembrane Protein 18 (TMM18) (C-Term) Antikörper (ABIN783829)

Target: Transmembrane Protein 18 (TMM18)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to Transmembrane protein 18.

Aufreinigung: Affinity chromatography

Immunogen: 15 amino acid peptide near the carboxy terminus of human TMEM18.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Antigendetails

Target: Transmembrane Protein 18 (TMM18)

Andere Bezeichnung: TMEM18

Hintergrund: Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.Synonyms: Transmembrane protein 18

Gen-ID: 129787

NCBI Accession: NP_690047

UniProt: Q96B42