EFCAB4A Antikörper (Center)

Produktnummer ABIN783783

Produktdetails anti-EFCAB4A Antikörper

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EFCAB4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects EFCAB4A at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human EFCAB4A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu EFCAB4A

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Andere Bezeichnung: EFCAB4A (EFCAB4A Produkte)

Synonyme: CRACR2B antikoerper, 6330520A15Rik antikoerper, BC026645 antikoerper, Cracr2a antikoerper, Efcab4 antikoerper, RGD1560911 antikoerper, zgc:158448 antikoerper, calcium release activated channel regulator 2B antikoerper, cracr2b antikoerper, CRACR2B antikoerper, Cracr2b antikoerper

Hintergrund: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.Synonyms: EF-hand calcium-binding domain-containing protein 4A

Gen-ID: 283229

NCBI Accession: NP_775855

UniProt: Q8N4Y2