PIWIL1 Antikörper (N-Term)

Produktnummer ABIN783767

Der Kaninchen Polyklonal Anti-PIWIL1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, PIWIL1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PIWIL1 Antikörper (N-Term) (ABIN783767)

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIWIL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PIWIL1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects PIWIL1 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the amino terminus of human PIWI-L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu PIWIL1

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Andere Bezeichnung: PIWIL1

Hintergrund: PIWI-L1 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L1 is thought to play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells as removing PIWI-L1 protein from single germline stem cells significantly decreases the rate of their division. Recent studies have shown that overexpression of PIWI-L1 (as well as other PIWI-like proteins) are potential biomarkers for colon and other cancers.Synonyms: HIWI, Piwi-like protein 1

Gen-ID: 9271

NCBI Accession: NP_001177900

UniProt: Q96J94