MFSD2B Antikörper (Center)
Kurzübersicht für MFSD2B Antikörper (Center) (ABIN783765)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Spezifität
- This antibody detects MFSD2B at Center.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, rat
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Aufreinigung
- Affinity chromatography purified via peptide column
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Immunogen
- 15 amino acid peptide near the center of human MFSD2B
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- MFSD2B (Major Facilitator Superfamily Domain Containing 2B (MFSD2B))
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Andere Bezeichnung
- MFSD2B
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Hintergrund
- Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
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Gen-ID
- 388931
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NCBI Accession
- NP_001073942
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UniProt
- A6NFX1
Target
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