PAPPA2 Antikörper (N-Term)

Produktnummer ABIN783757

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAPPA2 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für PAPPA2 Antikörper (N-Term) (ABIN783757)

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPPA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PAPPA2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects Pappalysin-2 / PAPPA2 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human PLAC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu PAPPA2

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Andere Bezeichnung: Pappalysin-2 / PAPPA2

Hintergrund: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.Synonyms: PAPP-A2, PAPP-E, PLAC3, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1

Gen-ID: 60676

NCBI Accession: NP_064714

UniProt: Q9BXP8