PLAC1 Antikörper (C-Term)

Produktnummer ABIN783753

Dieses Anti-PLAC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PLAC1 in WB und EIA. Geeignet für Human.

Kurzübersicht für PLAC1 Antikörper (C-Term) (ABIN783753)

Target: PLAC1 (Placenta-Specific 1 (PLAC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PLAC1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects PLAC1 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human PLAC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu PLAC1

Target: PLAC1 (Placenta-Specific 1 (PLAC1))

Andere Bezeichnung: PLAC1

Hintergrund: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.Synonyms: Placenta-specific protein 1

Gen-ID: 10761

NCBI Accession: NP_068568

UniProt: Q9HBJ0