TRIP6 Antikörper (Center)

Produktnummer ABIN783745

Produktdetails anti-TRIP6 Antikörper

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects TRIP6 / OIP1 at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human TRIP6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Andere Bezeichnung: TRIP6 / OIP1 (TRIP6 Produkte)

Synonyme: TRIP6 antikoerper, OIP-1 antikoerper, OIP1 antikoerper, TRIP-6 antikoerper, TRIP6i2 antikoerper, ZRP-1 antikoerper, thyroid hormone receptor interactor 6 antikoerper, TRIP6 antikoerper, Trip6 antikoerper

Hintergrund: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.Synonyms: OIP-1, OPA-interacting protein 1, TRIP-6, ZRP-1, Zyxin-related protein 1

Gen-ID: 7205

NCBI Accession: NP_003293

UniProt: Q15654

Pathways: Cell-Cell Junction Organization