NLRX1 Antikörper (N-Term)

Produktnummer ABIN783701

Der Kaninchen Polyklonal Anti-NLRX1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, NLRX1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für NLRX1 Antikörper (N-Term) (ABIN783701)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-NLRX1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects NLRX1 / NOD9 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the amino terminus of human NOD5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Andere Bezeichnung: NLRX1 / NOD9

Hintergrund: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production.Synonyms: Caterpiller 11.3, NLR family member X1, NOD26, NOD5, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9

Gen-ID: 79671

NCBI Accession: NP_078894

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interaktom