Der Kaninchen Polyklonal Anti-SESTD1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, SESTD1 in Proben von Human, Maus und Ratte zu detektieren.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target
SESTD1
(SEC14 and Spectrin Domains 1 (SESTD1))
Andere Bezeichnung
SESTD1 / SOLO
Hintergrund
SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1,4,5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.Synonyms: Huntingtin-interacting protein-like protein, SEC14 domain and spectrin repeat-containing protein 1