CRISP2 Antikörper (N-Term)

Produktnummer ABIN783679

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CRISP2 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CRISP2 Antikörper (N-Term) (ABIN783679)

Target: CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRISP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CRISP2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects CRISP2 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human CRISP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu CRISP2

Target: CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Andere Bezeichnung: CRISP2

Hintergrund: The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.Synonyms: CRISP-2, CT36, Cancer/testis antigen 36, Cysteine-rich secretory protein 2, GAPDL5, TPX1, Testis-specific protein TPX-1

Gen-ID: 7180

NCBI Accession: NP_001135879

UniProt: P16562