CCDC106 Antikörper (C-Term)

Produktnummer ABIN783671

Der Kaninchen Polyklonal Anti-CCDC106-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, CCDC106 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CCDC106 Antikörper (C-Term) (ABIN783671)

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC106 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CCDC106 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human CCDC106

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu CCDC106

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Andere Bezeichnung: CCDC106

Hintergrund: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.Synonyms: Coiled-coil domain-containing protein 106

Gen-ID: 29903

NCBI Accession: NP_037433

UniProt: Q9BWC9