SCUBE1 Antikörper (Center)

Produktnummer ABIN783649

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SCUBE1 in WB, IF und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SCUBE1 Antikörper (Center) (ABIN783649)

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCUBE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-SCUBE1 Antikörper

Bindungsspezifität: Center

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human SCUBE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: 14 amino acid peptide near the center of human SCUBE1

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SCUBE1

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Andere Bezeichnung: SCUBE1

Hintergrund: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1

Gen-ID: 80274

NCBI Accession: NP_766638

UniProt: Q8IWY4