TCTN2 Antikörper (C-Term)

Produktnummer ABIN783638

Der Kaninchen Polyklonal Anti-TCTN2-Antikörper wurde für WB und EIA validiert. Er ist geeignet, TCTN2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für TCTN2 Antikörper (C-Term) (ABIN783638)

Target: TCTN2 (Tectonic Family Member 2 (TCTN2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCTN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TCTN2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human TCTN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu TCTN2

Target: TCTN2 (Tectonic Family Member 2 (TCTN2))

Andere Bezeichnung: Tectonic-2

Hintergrund: TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49 % similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.Synonyms: C12orf38, TCTN2, TECT2

Gen-ID: 79867

NCBI Accession: NP_001137322

UniProt: Q96GX1

Pathways: Proton Transport