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SIRT3 Antikörper (Center)

SIRT3 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Huhn Polyclonal unconjugated
Produktnummer ABIN783622
  • Target Alle SIRT3 Antikörper anzeigen
    SIRT3 (Sirtuin 3 (SIRT3))
    Bindungsspezifität
    • 17
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 95
    • 43
    • 18
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 87
    • 16
    • 2
    • 2
    • 1
    Huhn
    Klonalität
    • 93
    • 16
    Polyklonal
    Konjugat
    • 60
    • 15
    • 12
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIRT3 Antikörper ist unkonjugiert
    Applikation
    • 95
    • 64
    • 43
    • 10
    • 9
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the center of human SIRT3
    Top Product
    Discover our top product SIRT3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    SIRT3 (Sirtuin 3 (SIRT3))
    Andere Bezeichnung
    SIRT3 (SIRT3 Produkte)
    Synonyme
    zgc:158774 antikoerper, sirtuin antikoerper, SIR2L3 antikoerper, 2310003L23Rik antikoerper, AI848213 antikoerper, Sir2l3 antikoerper, sirtuin 3 antikoerper, sirt3 antikoerper, SIRT3 antikoerper, Sirt3 antikoerper
    Hintergrund
    The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence, lifespan extension and several age-related diseases. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death.Synonyms: NAD-dependent deacetylase sirtuin-3 mitochondrial, SIR2-like protein 3, SIR2L3, SIRT-3, hSIRT3, sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae), sirtuin 3, sirtuin type 3, sirtuin-3
    Gen-ID
    23410
    NCBI Accession
    NP_001017524
    UniProt
    Q9NTG7
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