SIRT7 Antikörper (N-Term)

Produktnummer ABIN783618

Dieses Anti-SIRT7-Antikörper ist ein Huhn Polyklonal-Antikörper zur Detektion von SIRT7 in WB und EIA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für SIRT7 Antikörper (N-Term) (ABIN783618)

Target: SIRT7 (Sirtuin 7 (SIRT7))

Reaktivität: Human, Ratte, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser SIRT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SIRT7 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human SIRT7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SIRT7

Target: SIRT7 (Sirtuin 7 (SIRT7))

Andere Bezeichnung: SIRT7

Hintergrund: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.Synonyms: NAD-dependent deacetylase sirtuin-7, S.cerevisiae, SIR2-like protein 7, SIR2L7, SIRT-7, homolog) 7, sirtuin (silent mating type information regulation 2, sirtuin 7, sirtuin type 7, sirtuin-7

Gen-ID: 51547

NCBI Accession: NP_057622

UniProt: Q9NRC8