Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MORF4 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MORF4 in WB, IF, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN783556

Kurzübersicht für MORF4 Antikörper (N-Term) (ABIN783556)

Target

Alle MORF4 Antikörper anzeigen
MORF4 (Mortality Factor 4 (MORF4))

Reaktivität

  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 4
  • 2
Kaninchen

Klonalität

  • 4
  • 2
Polyklonal

Konjugat

  • 6
Dieser MORF4 Antikörper ist unkonjugiert

Applikation

  • 6
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, mouse, rat

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    18 amino acid peptide from near the amino terminus of human MORF4
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target

    MORF4 (Mortality Factor 4 (MORF4))

    Andere Bezeichnung

    MORF4

    Hintergrund

    Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.Synonyms: CSR, CSRB, SEN, SEN1, mortality factor 4

    UniProt

    Q9Y690
Sie sind hier:
Chat with us!