NUP160 Antikörper (C-Term)

Produktnummer ABIN783552

Dieses Anti-NUP160-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NUP160 in WB, IHC (p) und EIA. Geeignet für Maus, Human und Ratte.

Kurzübersicht für NUP160 Antikörper (C-Term) (ABIN783552)

Target: NUP160 (Nucleoporin 160kDa (NUP160))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP160 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-NUP160 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide from near the carboxy terminus of human NUP160

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu NUP160

Target: NUP160 (Nucleoporin 160kDa (NUP160))

Andere Bezeichnung: NUP160

Hintergrund: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.Synonyms: 160 kDa nucleoporin, KIAA0197, NUP120, Nuclear pore complex protein Nup160, Nucleoporin Nup160

Gen-ID: 23279

NCBI Accession: NP_056046

UniProt: Q12769

Pathways: Protein targeting to Nucleus