SPTLC2 Antikörper (C-Term)

Produktnummer ABIN783536

Der Kaninchen Polyklonal Anti-SPTLC2-Antikörper wurde für WB, IF, IHC (p) und EIA validiert. Er ist geeignet, SPTLC2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SPTLC2 Antikörper (C-Term) (ABIN783536)

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTLC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-SPTLC2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody recognizes Human SPTLC2. At least three isoforms of SPT2 are known to exist, this antibody will not detect isoform b. SPT2 antibody is predicted to not cross-react with SPT1.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.02 % Sodium Azide

Details zu SPTLC2

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Andere Bezeichnung: SPTLC2

Hintergrund: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.Synonyms: KIAA0526, LCB 2, LCB2, LCB2a, Long chain base biosynthesis protein 2, SPT 2, SPT2, Serine palmitoyltransferase 2, Serine-palmitoyl-CoA transferase 2

Gen-ID: 9517

NCBI Accession: NP_004854

UniProt: O15270