AP3B2 Antikörper (N-Term)

Produktnummer ABIN783508

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AP3B2 in WB, IF, IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für AP3B2 Antikörper (N-Term) (ABIN783508)

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP3B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-AP3B2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects AP3 complex subunit beta-2 (N-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Raised against an 18 amino acid peptide near the amino terminus of human AP3B2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu AP3B2

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Andere Bezeichnung: AP3 Complex Subunit beta-2

Hintergrund: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.Synonyms: AP-3 complex beta-2 subunit, AP3B2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 beta-2 subunit, Beta 3B Adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP, beta-NAP

Gen-ID: 8120

NCBI Accession: NP_004635

UniProt: Q13367