AP3M1 Antikörper (C-Term)
Kurzübersicht für AP3M1 Antikörper (C-Term) (ABIN783506)
Target
Alle AP3M1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody detects AP3 complex subunit mu-1 at C-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Affinity chromatography purified via peptide column
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Immunogen
- Raised against a 15 amino acid peptide near the carboxy terminus of human AP3M1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))
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Andere Bezeichnung
- AP3 Complex Subunit mu-1
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Hintergrund
- The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.Synonyms: AP-3 adapter complex mu3A subunit, AP3M1, Adapter-related protein complex 3 mu-1 subunit, Mu-adaptin 3A, Mu3A-adaptin
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Gen-ID
- 26985
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NCBI Accession
- NP_036227
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UniProt
- Q9Y2T2
Target
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