AP3S1 Antikörper (Center)

Produktnummer ABIN783504

Produktdetails anti-AP3S1 Antikörper

Target: AP3S1 (Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP3S1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: At least three isoforms of AP3S1 are known to exist, this antibody will detect the two larger isoforms. AP3S1 antibody is predicted to not cross-react with other AP3 protein family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Raised against a 19 amino acid peptide near the center of human AP3S1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu AP3S1

Target: AP3S1 (Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))

Andere Bezeichnung: AP3 Complex Subunit sigma-1 (AP3S1 Produkte)

Hintergrund: AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.Synonyms: AP-3 complex sigma-3A subunit, AP3S1, Adapter-related protein complex 3 sigma-1 subunit, CLAPS3, Clathrin-associated assembly/adapter protein, Sigma 3A Adaptin, Sigma-3A-adaptin, Sigma-adaptin 3a, small 3

Gen-ID: 1176

NCBI Accession: NP_001275

UniProt: Q92572